Coléus

Nom de la plante

Coléus

Dénomination latine internationale

Coleus forskohlii (Willd.) Brig.

Famille botanique

Lamiaceae

Description et habitat

• Plante herbacée originaire de l’Inde
• Cultivée en appartement

Parties utilisées

• Racines

Composition

Composants principaux de la plante

• Diterpène : forskoline

Propriétés

Propriétés de la plante

• La forskoline possède une action hypotensive et hypoagrégante plaquettaire intense
• Activité cardiotonique différente de celle de la caféine, de la digitale ou des Strophantus
• Aurait une action lipolytique comparable à celle de la caféine ou de l'éphédrine
• Stimulant thyroïdien (?)
• Actuellement en cours d’étude

Références bibliographiques

• Shonteh Henderson, Bahrat Magu, Chris Rasmussen, Stacey Lancaster, Chad Kerksick, Penny Smith, Charlie Melton, Patty Cowan, Mike Greenwood, Conrad Earnest, Anthony Almada, Pervis Milnor, Terri Magrans, Rodney Bowden, Song Ounpraseuth, Ashli Thomas, and Richard B Kreider. Effects of Coleus Forskohlii Supplementation on Body Composition and Hematological Profiles in Mildly Overweight Women. J Int Soc Sports Nutr. 2005; 2(2): 54–62. PMCID: PMC2129145 [1]
• Shirin Hasani-Ranjbar, Neda Nayebi, Bagher Larijani, and Mohammad Abdollahi. A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity. World J Gastroenterol. 2009 July 7; 15(25): 3073–3085. PMCID: PMC2705729 [2]
• Samuel A. Black, Jr. and Philip C. Trackman. Transforming Growth Factor-β1 (TGFβ1) Stimulates Connective Tissue Growth Factor (CCN2/CTGF) Expression in Human Gingival Fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent Mechanism: STATINS WITH FORSKOLIN BLOCK TGFβ1-INDUCED CCN2/CTGF EXPRESSION. J Biol Chem. 2008 April 18; 283(16): 10835–10847. PMCID: PMC2435243 [3]
• M R Bristow, R Ginsburg, A Strosberg, W Montgomery, and W Minobe. Pharmacology and inotropic potential of forskolin in the human heart. J Clin Invest. 1984 July; 74(1): 212–223. PMCID: PMC425203 [4]
• K B Seamon, W Padgett, and J W Daly. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc Natl Acad Sci U S A. 1981 June; 78(6): 3363–3367. PMCID: PMC319568 [5]
• D. Bowman and D. B. Hope. Forskolin: its effects on potassium-evoked release of vasopressin from the rat neurohypophysis. Br J Pharmacol. 1985 May; 85(1): 197–203. PMCID: PMC1916769 [6]