Acide caféique

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Nom de la substance

Acide caféique, caffeic acid, acide 3,4-dihydroxycinnamique

Famille moléculaire

Source végétale


Effet thérapeutique

Effets indésirables


  1. Beyer G, Melzig MF. Effects of selected flavonoids and caffeic acid derivatives on hypoxanthine-xanthine oxidase-induced toxicity in cultivated human cells. Planta Med. 2003 Dec;69(12):1125-9. PMID 14750029
  2. Chan WS, Wen PC, Chiang HC. Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition. Anticancer Res. 1995 May-Jun;15(3):703-7. PMID 7645946
  3. Oboh G, Agunloye OM, Adefegha SA, Akinyemi AJ, Ademiluyi AO. Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study. J Basic Clin Physiol Pharmacol. 2015 Mar;26(2):165-70. doi: 10.1515/jbcpp-2013-0141. PMID 24825096
  4. V. Pérez-Alvarez, R. A. Bobadilla, P. Muriel. Structure–hepatoprotective activity relationship of 3,4-dihydroxycinnamic acid (caffeic acid) derivatives. Journal of Applied Toxicology, Volume 21, Issue 6, pages 527–531, November/December 2001 [1]
  5. Bowels Bobby L & Miller, A.J. « Caffeic Acid Activity Against Clostridium botulinum Spores. Journal of Food Science (1994, volume 59, partie 4, p 905), Blackwell Publishing.
  6. Chiang LC, Chiang W, Chang MY, Ng LT, Lin CC. Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Res. 2002 Jul;55(1):53-62. PMID 12076751
  7. Chung MJ, Walker PA, Hogstrand C. Dietary phenolic antioxidants, caffeic acid and Trolox, protect rainbow trout gill cells from nitric oxide-induced apoptosis. Aquat Toxicol. 2006 Dec 30;80(4):321-8. PMID 17113165
  8. MARINOVA Emma M, TONEVA A, YANISHLIEVA N. Comparison of the antioxidative properties of caffeic and chlorogenic acids. Food chemistry, 2009, vol. 114, no4, pp. 1498-1502
  9. K. Ghedira, P. Goetz, R. Le Jeune. Propolis. Phytothérapie 2009, Volume 7, Number 2, 100-105