Carraghénates
(Redirigé depuis Carraghénate)
Nom de la substance
Carraghénates, carraghénanes
Famille moléculaire
- Les carraghénanes (kappa, lambda, iota) sont des polysaccharides sulfatés isolés d'algues marines
Source végétale
- Algues rouges (Chondrus crispus)
Propriétés
- Activité antivirale [1], [2]
- Diminue la réplication du virus de l’hépatite A in vitro [3]
- Inhibition de la croissance des Papillomavirus in vitro [4]
- Réduction de la charge virale de Rhinovirus dans les sécrétions nasales d’enfants enrhumés [5]
Effet thérapeutique
- Virustatique d'usage local
Effets indésirables
Bibliographie
- ↑ González ME, Alarcón B, Carrasco L. Polysaccharides as antiviral agents: antiviral activity of carrageenan. Antimicrob Agents Chemother. 1987 Sep;31(9):1388-93. doi: 10.1128/AAC.31.9.1388. PMID 2823697; PMCID: PMC174948.
- ↑ Álvarez-Viñas M, Souto S, Flórez-Fernández N, Torres MD, Bandín I, Domínguez H. Antiviral Activity of Carrageenans and Processing Implications. Mar Drugs. 2021 Jul 30;19(8):437. doi: 10.3390/md19080437. PMID 34436276; PMCID: PMC8400836.
- ↑ Girond S, Crance JM, Van Cuyck-Gandre H, Renaudet J, Deloince R. Antiviral activity of carrageenan on hepatitis A virus replication in cell culture. Res Virol. 1991 Jul-Aug;142(4):261-70. doi: 10.1016/0923-2516(91)90011-q. PMID 1665574.
- ↑ Buck CB, Thompson CD, Roberts JN, Müller M, Lowy DR, Schiller JT. Carrageenan is a potent inhibitor of papillomavirus infection. PLoS Pathog. 2006 Jul;2(7):e69. doi: 10.1371/journal.ppat.0020069. PMID 16839203; PMCID: PMC1500806.
- ↑ Fazekas T, Eickhoff P, Pruckner N, Vollnhofer G, Fischmeister G, Diakos C, Rauch M, Verdianz M, Zoubek A, Gadner H, Lion T. Lessons learned from a double-blind randomised placebo-controlled study with a iota-carrageenan nasal spray as medical device in children with acute symptoms of common cold. BMC Complement Altern Med. 2012 Sep 5;12:147. doi: 10.1186/1472-6882-12-147. PMID 22950667; PMCID: PMC3575307.
- ↑ Thomson AW, Fowler EF. Carrageenan: a review of its effects on the immune system. Agents Actions. 1981 May;11(3):265-73. doi: 10.1007/BF01967625. PMID 7020378.
- ↑ Thomson AW. Carrageenan and the immune response. Biomedicine. 1978 May-Jun;28(3):148-52. PMID 359059 Review.
- ↑ Thomson AW, Wilson AR, Cruickshank WJ, Horne CH. Evaluation of carrageenan as an immunosuppressive agent and mediator of intravascular coagulation. Biomedicine. 1976 May;24(2):102-6. PMID 776242