Calophyllolide

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Nom de la substance

Calophyllolide

Famille moléculaire

Source végétale

Propriétés

  • Anticoagulant [3]
  • Anti-inflammatoire [4] et protecteur capillaire [5]
  • Augmente la différentiation des ostéoblastes [6]
  • Vulnéraire, cicatrisant, protecteur et anti-inflammatoire cutané [7], [8], [9], potentialités dans la dermatite atopique [10]

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Kunesch, G., & Polonsky, J. (1967). On the biosynthesis of neoflavanoids: calophyllolide (4-phenylcoumarin). Chemical Communications (London), (7), 317-318.
  2. Gerhard Kunesch, Judith Polonsky. Biosynthese du calophyllolide (neoflavanoide) sur l'origine biogenetique du groupement tigloyle. Phytochemistry, Volume 8, Issue 7, 1969, Pages 1221-1226, https://doi.org/10.1016/S0031-9422(00)85561-2.
  3. R B Arora, C N Mathur, S D S Seth, Calophyllolide, a complex coumarin anticoagulant from Calophyllum inophyllum Linn, Journal of Pharmacy and Pharmacology, Volume 14, Issue 1, September 1962, Pages 534–535, https://doi.org/10.1111/j.2042-7158.1962.tb11133.x
  4. Nguyen, V. L., Truong, C. T., Nguyen, B. C. Q., Vo, T. N. V., Dao, T. T., Nguyen, V. D., ... & Bui, C. B. (2017). Anti-inflammatory and wound healing activities of calophyllolide isolated from Calophyllum inophyllum Linn. PloS one, 12(10), e0185674.
  5. Saxena RC, Nath R, Palit G, Nigam SK, Bhargava KP. Effect of calophyllolide, a nonsteroidal anti-inflammatory agent, on capillary permeability. Planta Med. 1982 Apr;44(4):246-8. doi: 10.1055/s-2007-971459. PMID 7100303.
  6. Liu WH, Liu YW, Chen ZF, Chiou WF, Tsai YC, Chen CC. Calophyllolide content in Calophyllum inophyllum at different stages of maturity and its osteogenic activity. Molecules. 2015 Jul 7;20(7):12314-27. doi: 10.3390/molecules200712314. PMID 26198219; PMCID: PMC6332356.
  7. Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Cassien M, Mercier A, Thétiot-Laurent S, Culcasi M, Ricquebourg E, Asteian A, Herbette G, Bianchini JP, Raharivelomanana P, Pietri S. Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts. Antioxidants (Basel). 2021 Jan 30;10(2):199. doi: 10.3390/antiox10020199. PMID 33573143
  8. Ansel JL, Lupo E, Mijouin L, Guillot S, Butaud JF, Ho R, Lecellier G, Raharivelomanana P, Pichon C. Biological Activity of Polynesian Calophyllum inophyllum Oil Extract on Human Skin Cells. Planta Med. 2016 Jul;82(11-12):961-6. doi: 10.1055/s-0042-108205. PMID 27280931
  9. Erdogan SS, Gur TF, Terzi NK, Dogan B. Evaluation of the cutaneous wound healing potential of tamanu oil in wounds induced in rats. J Wound Care. 2021 Sep 2;30(Sup9a):Vi-Vx. doi: 10.12968/jowc.2021.30.Sup9a.V. PMID 34597168
  10. Pribowo A, Girish J, Gustiananda M, Nandhira RG, Hartrianti P. Potential of Tamanu (Calophyllum inophyllum) Oil for Atopic Dermatitis Treatment. Evid Based Complement Alternat Med. 2021 Dec 26;2021:6332867. doi: 10.1155/2021/6332867. PMID 35069754; PMCID: PMC8782620.