Savinine

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Nom de la substance

Savinine (= isohibalactone)

Famille moléculaire

Source végétale

Propriétés

  • Neuroprotecteur [2]
  • Inhibition des protéases du coronavirus SARS-CoV [3]

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Song Y, Deng Y, Huang D, Wen J, Liu Z, Li F. LC-MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. J Ethnopharmacol. 2012 Jun 14;141(3):957-63. doi: 10.1016/j.jep.2012.03.034. PMID 22497733
  2. Li XJ, Kim KW, Oh H, Liu XQ, Kim YC. Chemical Constituents and an Antineuroinflammatory Lignan, Savinin from the Roots of Acanthopanax henryi. Evid Based Complement Alternat Med. 2019 Feb 21;2019:1856294. doi: 10.1155/2019/1856294. eCollection 2019. PMID 30915141
  3. Pillaiyar T, Manickam M, Namasivayam V, Hayashi Y, Jung SH. An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy. J Med Chem. 2016 Jul 28;59(14):6595-628. doi: 10.1021/acs.jmedchem.5b01461. PMID 26878082