Acide ginkgolique

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Nom de la substance

Acide ginkgolique, acides ginkgoliques

Famille moléculaire

Acides alkylphénoliques

Source végétale

Ginkgo biloba

Propriétés

Effet thérapeutique

Effets indésirables

  • Toxicité hépatique [4] et néphrotoxique [1]
  • Cytotoxique et potentiellement cancérogène [5]

Bibliographie

  1. 1,0 et 1,1 Shao, Y., Chen, Y., Zhu, Q., Yi, L., Ma, Y., Zang, X., & Yao, W. (2025). The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba. The American Journal of Chinese Medicine, 53(01), 147-177.
  2. Boateng, I. D. (2022). A critical review of ginkgolic acids in Ginkgo biloba leaf extract (EGb): toxicity and technologies to remove ginkgolic acids and their promising bioactivities. Food & Function, 13(18), 9226-9242.
  3. Biernacka P, Adamska I, Felisiak K. The Potential of Ginkgo biloba as a Source of Biologically Active Compounds-A Review of the Recent Literature and Patents. Molecules. 2023 May 9;28(10):3993. doi: 10.3390/molecules28103993. PMID 37241734; PMCID: PMC10222153.
  4. Liu, Z. H., & Zeng, S. (2009). Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes. Toxicology letters, 187(3), 131-136.
  5. Mei, N., Guo, X., Ren, Z., Kobayashi, D., Wada, K., & Guo, L. (2017). Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports. Journal of Environmental Science and Health, Part C, 35(1), 1-28.