Diosmine

De WikiPhyto
Sauter à la navigation Sauter à la recherche

Nom de la substance

Diosmine, diosmin (anglais)

Famille moléculaire

Flavonoïde (flavone)

Source végétale

Propriétés

  • Veinotonique [1]
  • Anti-oxydant, s'oppose au mécanisme d'ischémie-reperfusion [2], [3]
  • Prévention de la carcinogenèse (cancer du colon) [4]
  • Prévention de la neuropathie diabétique [5]

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Benavente-García O, Castillo J. Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity. J Agric Food Chem. 2008 Aug 13;56(15):6185-205. doi: 10.1021/jf8006568. PMID 18593176
  2. Senthamizhselvan O, Manivannan J, Silambarasan T, Raja B. Diosmin pretreatment improves cardiac function and suppresses oxidative stress in rat heart after ischemia/reperfusion. Eur J Pharmacol. 2014 Apr 24;736C:131-137. doi: 10.1016/j.ejphar.2014.04.026. PMID 24769512
  3. Liu X, Zhang X, Zhang J, Kang N, Zhang N, Wang H, Xue J, Yu J, Yang Y, Cui H, Cui L, Wang L, Wang X. Diosmin protects against cerebral ischemia/reperfusion injury through activating JAK2/STAT3 signal pathway in mice. Neuroscience. 2014 May 30;268:318-27. doi: 10.1016/j.neuroscience.2014.03.032. PMID 24680937
  4. Tanaka T, Kohno H, Mori H. Chemoprevention of Colon Carcinogenesis by Dietary Non-nutritive Compounds. Asian Pac J Cancer Prev. 2001;2(3):165-177. PMID 12718627 Texte intégral
  5. Jain D, Bansal MK, Dalvi R, Upganlawar A, Somani R. Protective effect of diosmin against diabetic neuropathy in experimental rats. J Integr Med. 2014 Jan;12(1):35-41. doi: 10.1016/S2095-4964(14)60001-7. PMID 24461593
  • Patel K, Gadewar M, Tahilyani V, Patel DK. A review on pharmacological and analytical aspects of diosmetin: a concise report. Chin J Integr Med. 2013 Oct;19(10):792-800. doi: 10.1007/s11655-013-1595-3. PMID 24092244