Mangiférine

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Nom de la substance

Mangiférine

Famille moléculaire

Source végétale

Propriétés

  • Hypoglycémiant [1]
  • Antioxydant
  • Antiviral [2], potentialités contre le virus de la dengue [3], du SARS-CoV-2 [4]
  • Anti-inflammatoire

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Singh AK, Raj V, Keshari AK, Rai A, Kumar P, Rawat A, Maity B, Kumar D, Prakash A, De A, Samanta A, Bhattacharya B, Saha S. Isolated mangiferin and naringenin exert antidiabetic effect via PPARγ/GLUT4 dual agonistic action with strong metabolic regulation. Chem Biol Interact. 2018 Jan 25;280:33-44. doi: 10.1016/j.cbi.2017.12.007. PMID 29223569.
  2. Santhi VP, Masilamani P, Sriramavaratharajan V, Murugan R, Gurav SS, Sarasu VP, Parthiban S, Ayyanar M. Therapeutic potential of phytoconstituents of edible fruits in combating emerging viral infections. J Food Biochem. 2021 Jul 8;45(8):e13851. doi: 10.1111/jfbc.13851. Epub ahead of print. PMID 34236082; PMCID: PMC8420441.
  3. Kalaimathi K, Rani JMJ, Vijayakumar S, Prakash N, Karthikeyan K, Thiyagarajan G, Bhavani K, Prabhu S, Varatharaju G. Anti-dengue Potential of Mangiferin: Intricate Network of Dengue to Human Genes. Rev Bras Farmacogn. 2022;32(3):410-420. doi: 10.1007/s43450-022-00258-6. PMID 35572718; PMCID: PMC9078210.
  4. Junior AG, Tolouei SEL, Dos Reis Lívero FA, Gasparotto F, Boeing T, de Souza P. Natural Agents Modulating ACE-2: A Review of Compounds with Potential against SARS-CoV-2 Infections. Curr Pharm Des. 2021;27(13):1588-1596. doi: 10.2174/1381612827666210114150607. PMID 33459225.