Sempervirol
Aller à la navigation
Aller à la recherche
Nom de la substance
Sempervirol
Famille moléculaire
Source végétale
Propriétés
- Le 7-céto-sempervirol possède des propriétés antiparasitaires et anthelmintiques (Schistosoma mansoni et Fasciola hepatica) [2], [3]
- Propriétés antituberculeuses [4]
Effet thérapeutique
Effets indésirables
Bibliographie
- ↑ L.Mangoni, R. Caputo. Sempervirol, a novel type of diterpene phenol. Tetrahedron Letters, Volume 8, Issue 8, 1967, Pages 673-675 https://doi.org/10.1016/S0040-4039(00)90571-9
- ↑ Edwards J, Brown M, Peak E, Bartholomew B, Nash RJ, et al. (2015) The Diterpenoid 7-Keto-Sempervirol, Derived from Lycium chinense, Displays Anthelmintic Activity against both Schistosoma mansoni and Fasciola hepatica. PLOS Neglected Tropical Diseases 9(3): e0003604. https://doi.org/10.1371/journal.pntd.0003604
- ↑ Alessandra Crusco, Cinzia Bordoni, Anand Chakroborty, Kezia C.L. Whatley, Helen Whiteland, Andrew D. Westwell, Karl F.Hoffmann. Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues. European Journal of Medicinal Chemistry, Volume 152, 25 May 2018, Pages 87-100 https://doi.org/10.1016/j.ejmech.2018.04.032
- ↑ Ulubelen A, Topcu G, Johansson CB. Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. J Nat Prod. 1997 Dec;60(12):1275-80. PMID 9428161