Taspine
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Sommaire
Nom de la substance
Taspine
Famille moléculaire
Source végétale
Propriétés
- Immunomodulant
- Vulnéraire et cicatrisant [1], [2], [3]
- Inhibiteur de la cholinestérase [4]
- Anti-angiogénique [5]
Effet thérapeutique
Effets indésirables
Bibliographie
- ↑ Vaisberg AJ, Milla M, Planas MC, Cordova JL, de Agusti ER, Ferreyra R, Mustiga MC, Carlin L, Hammond GB. Taspine is the cicatrizant principle in Sangre de Grado extracted from Croton lechleri. Planta Med. 1989 Apr;55(2):140-3. doi: 10.1055/s-2006-961907. PMID 2748730.
- ↑ Porras-Reyes BH, Lewis WH, Roman J, Simchowitz L, Mustoe TA. Enhancement of wound healing by the alkaloid taspine defining mechanism of action. Proc Soc Exp Biol Med. 1993 May;203(1):18-25. doi: 10.3181/00379727-203-43567. PMID 8386382.
- ↑ Dong Y, He L, Chen F. [Enhancement of wound healing by taspine and its effect on fibroblast]. Zhong Yao Cai. 2005 Jul;28(7):579-82. Chinese. PMID 16252727.
- ↑ Rollinger, J. M., Schuster, D., Baier, E., Ellmerer, E. P., Langer, T., & Stuppner, H. (2006). Taspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana. Journal of natural products, 69(9), 1341–1346. https://doi.org/10.1021/np060268p. PMID 16989531
- ↑ Zhang J, Zhang Y, Zhang S, Wang S, He L. Discovery of novel taspine derivatives as antiangiogenic agents. Bioorg Med Chem Lett. 2010 Jan 15;20(2):718-21. doi: 10.1016/j.bmcl.2009.11.073. Epub 2009 Dec 14. Erratum in: Bioorg Med Chem Lett. 2010 Mar 1;20(5):1797. PMID 20006929.
