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Nom de la substance


Famille moléculaire

Source végétale


  • Hypolipidémiant [7], inhibe l'accumulation de lipides dans les hépatocytes [8]

Effet thérapeutique

Effets indésirables


  1. Bogacheva, N. G., Kiselev, V. P., & Kogan, L. M. (1976). Isolation of 3, 26 bisglycoside of yamogenin from Trigonella foenum graecum. Chemistry of natural compounds.
  2. Hardman, R. O. L. A. N. D., & Jefferies, T. M. (1971). The determination of diosgenin and yamogenin in fenugreek seed by combined column chromatography and infrared spectrometry. The Journal of pharmacy and pharmacology, 23, 231S.
  3. Dawidar, A. M., Saleh, A. A., & Elmotei, S. L. (1973). Steroid sapogenin constituents of fenugreek seeds. Planta medica, 24(08), 367-370.
  4. Hardman, R., & Sofowora, E. A. (1970). Isolation and characterization of yamogenin from Balanites aegyptiaca. Phytochemistry, 9(3), 645-649.
  5. Da Costa, F. F., & Mukherjee, R. (1984). Diosgenin and yamogenin from Dioscorea multiflora. Journal of Natural Products, 47(5), 909-910.
  6. Blunden, G., Yi, Y., & Jewers, K. (1978). Steroidal sapogenins from leaves of Agaveae species. Phytochemistry, 17(11), 1923-1925.
  7. Shahina, S. M., Jahan, B., Niaz, K., Khokhar, A., & Ghaffar, A. (2019). Use of diosgenin, yamogenin, tigogenin and neotigogenin for treatment of hyperlipidemia by inhibiting cholesterol absorption in git. Pharmaceutical Research, 4(2), 34-37.
  8. Moriwaki, S., Murakami, H., Takahashi, N., Uemura, T., Taketani, K., Hoshino, S., ... & Kawada, T. (2014). Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes. Bioscience, biotechnology, and biochemistry, 78(7), 1231-1236.
  • Puri, H. S., Jefferies, T. M., & Hardman, R. (1976). Diosgenin and yamogenin levels in some Indian plant samples. Planta Medica, 30(06), 118-121. PMID 981383