Paracymène

De WikiPhyto

Nom de la substance

Paracymène, p-cymène, para-cymène, p-cymene

Famille moléculaire

Source végétale

Propriétés

Effet thérapeutique

Effets indésirables

  • En forte dose, céphalées, nausées, vomissements
  • Le paracymène à la concentration de 4% dans la vaseline n'a provoqué aucune réaction de sensibilisation allergique chez 25 volontaires Toxnet

Bibliographie

  1. Kiskó G, Roller S. Carvacrol and p-cymene inactivate Escherichia coli O157:H7 in apple juice. BMC Microbiology. 2005;5:36. doi:10.1186/1471-2180-5-36. texte intégral
  2. Walde A, Ve B, Scheline RR, Monge P. p-Cymene metabolism in rats and guinea-pigs. Xenobiotica. 1983 Aug;13(8):503-12. PMID 6649683
  3. Austgulen LT, Solheim E, Scheline RR. Metabolism in rats of p-cymene derivatives: carvacrol and thymol. Pharmacol Toxicol. 1987 Aug;61(2):98-102. PMID 2959918
  4. Alavinezhad A, Boskabady MH. Antiinflammatory, antioxidant, and immunological effects of Carum copticum L. and some of its constituents. Phytother Res. 2014 Dec;28(12):1739-48. doi: 10.1002/ptr.5200. PMID 25044318
  5. G. Xie, N. Chen, L.W. Soromou, F. Liu, Y. Xiong, Q. Wu, H. Li, H. Feng, G. Liu. p-Cymene protects mice against lipopolysaccharide-induced acute lung injury by inhibiting inflammatory cell activation. Molecules, 17 (2012), pp. 8159–8173
  6. Quintans Jde S, Menezes PP, Santos MR, Bonjardim LR, Almeida JR, Gelain DP, Araújo AA, Quintans-Júnior LJ. Improvement of p-cymene antinociceptive and anti-inflammatory effects by inclusion in β-cyclodextrin. Phytomedicine. 2013 Mar 15;20(5):436-40. doi: 10.1016/j.phymed.2012.12.009. PMID 23357360
  7. L.R. Bonjardim, E.S. Cunha, A.G. Guimarães, M.F. Santana, M.G.B. Oliveira, M.R. Serafini, et al. Evaluation of the anti-inflammatory and antinociceptive properties of p-Cymene in Mice. Zeitschrift Fur Naturforschung C, 67 (2012), pp. 15–21
  8. Quintans-Júnior L, Moreira JCF, Pasquali MAB, et al. Antinociceptive Activity and Redox Profile of the Monoterpenes (+)-Camphene, p-Cymene, and Geranyl Acetate in Experimental Models. ISRN Toxicology. 2013;2013:459530. doi:10.1155/2013/459530. texte intégral
  9. M.F. Santana, L.J. Quintans-Júnior, S.C.H. Cavalcanti, M.G.B. Oliveira, A.G. Guimarães, E.S. Cunha, et al. p-cymene reduces orofacial nociceptive response in mice. Revista Brasileria Farmacogen, 21 (2011), pp. 1138–1143 texte intégral
  10. Silva MTM, Ribeiro FPRA, Medeiros MAMB, et al. The Vasorelaxant Effect of p-Cymene in Rat Aorta Involves Potassium Channels. The Scientific World Journal. 2015;2015:458080. doi:10.1155/2015/458080. texte intégral
  • Pauly G, Gleizes M, Bernard-Dagan C. Identification des constituants de l'essence des aiguilles de Pinus pinaster. Phytochemistry, Volume 12, Issue 6, June 1973, Pages 1395-1398