Verbénone

De WikiPhyto

Nom de la substance

Verbénone

Famille moléculaire

Cétone monoterpénique bicyclique

Source végétale

Propriétés

  • Expectorant
  • Phéromone [1]
  • Insecticide [2], [3]
  • Hydroxylé par le cytochrome P450 (CYP2A6) [4]

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Rudinsky J. A. Multiple Functions of the Southern Pine Beetle Pheromone Verbenone. Environmental Entomology, Volume 2, Number 4, August 1973 , pp. 511-514(4)
  2. Gene D. Amman, Ralph W. Thier, Mark D. McGregor, Richard F. Schmitz. Efficacy of verbenone in reducing lodgepole pine infestation by mountain pine beetles in Idaho. Revue canadienne de recherche forestière, 1989, 19(1): 60-64, [1]
  3. John H Borden, Leslie J Chong, Tracy J Earle, Dezene P.W. Huber. Protection of lodgepole pine from attack by the mountain pine beetle, Dendroctonus ponderosae (Coleoptera: Scolytidae) using high doses of verbenone in combination with nonhost bark volatiles. The Forestry Chronicle, 2003, 79(3): 685-691
  4. Miyazawa M, Sugie A, Shimada T. Roles of human CYP2A6 and 2B6 and rat CYP2C11 and 2B1 in the 10-hydroxylation of (-)-verbenone by liver microsomes.Drug Metab Dispos. 2003 Aug;31(8):1049-53. PMID 12867494
  • Uzi Ravid, Eli Putievsky, Irena Katzir, Efraim Lewinsohn, Nativ Dudai. Identification of (1R)(+)-Verbenone in Essential Oils of Rosmarinus officinalis L. Flavour and Fragrance Journal, Volume 12, Issue 2, pages 109–112, March 1997
  • Mitsuo MIYAZAWA, Atsushi SUGIE and Masaki SHINDO, “Biotransformation of (−)-Verbenone by Human Liver Microsomes”, Biosci. Biotechnol. Biochem., Vol. 66, 2458-2460 (2002). [2]