Falcarindiol

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Nom de la substance

Falcarindiol

Famille moléculaire

Source végétale

Propriétés

  • Antifongique [1], [2]
  • Antibactérien [3], [4]
  • Inhibe la croissance de l’adénocarcinome gastrique humain MK-1 [5]
  • Antimutagène [6]

Effet thérapeutique

Effets indésirables

Bibliographie

  1. Villegas M, Vargas D, Msonthi JD, Marston A, Hostettmann K. Isolation of the antifungal compounds falcarindiol and sarisan from Heteromorpha trifoliata. Planta Med. 1988 Feb;54(1):36-7. PMID 3375335
  2. Garrod, B., Lea, E. J. A., & Lewis, B. G. (1979). Studies on the mechanism of action of the antifungal compound falcarindiol. New Phytologist, 83(2), 463-471.
  3. Muir AD, Cole AL, Walker JR. Antibiotic compounds from New Zealand plants. I. Falcarindiol, an anti-dermatophyte agent from Schefflera digitata. Planta Med. 1982 Mar;44(3):129-33. PMID 7089093
  4. Matsuura H, Saxena G, Farmer SW, Hancock RE, Towers GH. Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa. Planta Med. 1996 Jun;62(3):256-9. PMID 8693041
  5. Fujioka, T., Furumi, K., Fujii, H., Okabe, H., Mihashi, K., Nakano, Y., ... & Mori, M. (1999). Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica. Chemical and pharmaceutical bulletin, 47(1), 96-100.
  6. Miyazawa, M., Shimamura, H., Bhuva, R. C., Nakamura, S. I., & Kameoka, H. (1996). Antimutagenic activity of falcarindiol from Peucedanum praeruptorum. Journal of agricultural and food chemistry, 44(11), 3444-3448.